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KMID : 0361020170600070356
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Korean Journal of Otolaryngology - Head and Neck Surgery
2017 Volume.60 No. 7 p.356 ~ p.359
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A Case of Metastatic Hepatocellular Carcinoma Mimicking Acute Cervical Lymphadenitis
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Choi Yoon-Seok
Bae Chang-Hoon
Kim Yong-Dae
Song Si-Youn
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Abstract
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Hepatocellular carcinoma (HCC) is the most common cancer of the liver and the fifth most common cancer worldwide. The sites of extrahepatic metastasis are usually the lungs, adrenal gland, bone and brain via hematogeneous spreads. The lymphatic spread of HCC, mostly occurring at the regional abdominal lymph nodes, is relatively rare. Cervical lymph node metastasis of HCC is a very rare presentation, so that it is easily neglected in the clinic. In some cases, differential diagnosis between cervical lymphadenitis and lymph node metastasis can be challenging due to similar clinical features such as rapidly growing pattern, tenderness, fever and general ache. We report a case of left cervical lymphadenopathy diagnosed as HCC without prior diagnosis of HCC. A core-needle biopsy of left cervical lymphadenopathy demonstrated poorly differentiated unknown primary metastatic cancer. Positron emission tomography-computed tomography revealed the liver as the primary site of metastasis and the pathologic examination of liver biopsy specimen determined it to be HCC.
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KEYWORD
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Acute lymphadenitis, Cervical lymph node metastasis, Hepatocellular carcinoma
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